The North America natural killer (NK) cell therapeutics market comprises features such as the increasing need for better therapeutics options that will impact the launching of a new product by manufacturers into the market enhancing its demand as well as increasing investment in RD leading to the market growth. Currently, various research studies are taking place which is expected to create a competitive advantage for manufacturers to develop new and innovative NK cell therapies, which is expected to provide various other opportunities for market growth. However, the lack of specificity and poor in-vivo survival of the cells, and the high cost associated with therapies are expected to restrain market growth in the forecast period.
The North America natural killer (NK) cell therapeutics market is supportive and aims to reduce the progression of the disease. Data Bridge Market Research analyzes that North America natural killer (NK) cell therapeutics market will grow at a CAGR of 42.6% during the forecast period of 2023 to 2030.
The North America natural killer (NK) cell therapeutics market report provides details of market share, new developments, product pipeline analysis, the impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, product approvals, strategic decisions, product launches, geographic expansions, and technological innovations in the market. To understand the analysis and the market scenario, contact us for an analyst brief, our team will help you create a revenue-impact solution to achieve your desired goal.
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North America Natural Killer (NK) Cell Therapeutics Market Regional Analysis/Insights
The North America natural killer (NK) cell therapeutics market is categorized into five notable segments: therapeutics, approaches, application, end-user, and distribution channel.
The countries covered in this market report are the U.S., Canada, and Mexico.
The U.S. is dominating the North America natural killer (NK) cell therapeutics market and is expected to grow due to the rise in technological advancement in the market.
The country section of the report also provides individual market-impacting factors and changes in regulation in the market domestically that impact the current and future trends of the market. Data points such as new sales, replacement sales, country demographics, regulatory acts, and import-export tariffs are some of the major pointers used to forecast the market scenario for individual countries. Also, the presence and availability of North America brands and their challenges faced due to large or scarce competition from local and domestic brands, and the impact of sales channels are considered while providing forecast analysis of the country data.
Recent Developments
- In January 2022, Takeda acquired Adaptate biotherapeutics to develop novel gamma delta (γδ) T cell engager therapies targeting solid tumors. Through the acquisition, Takeda will obtain Adaptate’s antibody-based γδ T cell engager platform, including pre-clinical candidate and discovery pipeline programs. Adaptate’s γδ T cell engagers are designed to specifically modulate γδ T cell-mediated immune responses at tumor sites while sparing damage to healthy cells. This acquisition helped the company to focus on RD.
- In December 2021, Nektar Therapeutics announced phase 1b data for novel T regulatory cell stimulator NKTR-358 (LY3471851) in patients with atopic dermatitis. NKTR-358 is designed to treat autoimmune and inflammatory conditions by correcting the immune system imbalance that results from increased levels of inflammatory T cells and reduced numbers and impaired function of immune regulating Treg cells. This has helped the company to focus on RD for further phases.
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Competitive Landscape and North America Natural Killer (NK) Cell Therapeutics Market Share Analysis
The North America natural killer (NK) cell therapeutics market competitive landscape provides details of competitors. Details included are company overview, company financials, revenue generated, market potential, investment in RD, new market initiatives, North America presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, and application dominance. The above data points provided are only related to the companies' focus related to the market.
Some of the major players operating in the North America natural killer (NK) cell therapeutics market are Merck KGaA, Bristol-Myers Squibb Company, Glycostem, Sanofi, Cytovia Therapeutics, ImmunityBio, Inc., Biohaven Pharmaceuticals, Fate Therapeutics, EMERcell, Phio Pharmaceuticals, PersonGen BioTherapeutics, Innate Pharma, Inc., INmuneBIO, Gamida Cell, Acepodia Inc., Affimed GmbH, Multimmune GmbH, iCell Gene Therapeutics, Takeda Pharmaceutical Company Limited, and Regeneron Pharmaceuticals Inc. among others.
Market Definition
Natural killer (NK) cells are large granular lymphocytes that have the ability to quickly respond to a pathological challenge. They are important components of the innate immune system and play an important role in generating an immune response against malignancies and infectious diseases caused by viral pathogens. They have been recognized to induce the direct killing of targeted cells involving cancer cells. They have the ability to recognize the multitude of infected cells without being dependent on a single antigen-expressing cell.
NK cells secrete cytokines and chemokines that recruit other immune cells such as T cells and B cells, which enhances the immune response against the tumor cells. As NK cells do not express T cell receptors, they induce a low risk of graft-versus-host disease. Moreover, iPSC cell lines derived NK cell therapy , CAR-NK therapy, overcomes the need for a long and complex manufacturing process that allows patients with aggressive tumors to afford tumor treatment as soon as possible. Along with this iPSC derived NK cells can be infused repeatedly, which enhances the immune response with dose regulation.
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